Friday, May 17, 2019

A new method for glycosylation based site-specific conjugation? Look out Synaffix

Here is a novel approach to combine a transglutaminase process to incorporate a conjugation site at the Q295 site in place of the glycosylation site.  Sounds a lot like Synaffix tech to me.

Thiolation of Q295: Site-specific conjugation of hydrophobic payloads without the need for genetic engineering.

What do you think?

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